Association of chronotropic incompetence with echocardiographic ischemia and prognosis

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Association of chronotropic incompetence with echocardiographic ischemia and prognosis.

OBJECTIVES This study sought to examine the prognostic importance of chronotropic incompetence among patients referred for stress echocardiography. BACKGROUND Although chronotropic incompetence has been shown to be predictive of an adverse prognosis, it is not clear if this association is independent of exercise-induced myocardial ischemia. METHODS Consecutive patients (146 men and 85 women...

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Echocardiographic predictors of chronotropic incompetence to exercise in patients with heart failure with preserved ejection fraction.

OBJECTIVE Exercise intolerance in patients with heart failure with preserved ejection fraction (HFpEF) is most often attributed to diastolic dysfunction (DD); however, chronotropic incompetence (CI) could also play an important role. We intended to examine whether there are predictive echocardiographic parameters of DD for impaired chronotropic response to exercise. METHODS AND RESULTS Patien...

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Chronotropic incompetence in heart failure.

The relationship between heart rate (HR) during exercise and exercise capacity in patients with heart failure due to left ventricular systolic dysfunction remains unclear. The accepted diagnostic criterion for chronotropic incompetence (CI), a maximum agepredicted heart rate (MA-PHR) 85%, is seen in 50% of patients with severe heart failure on contemporary medical therapy (1). Whether the lesse...

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Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography

BACKGROUND Exercise echocardiography (EE) is an established method to diagnose coronary artery disease (CAD). Chronotropic incompetence (CI) during the EE may be a marker of myocardial ischemia. The purpose of this investigation was to evaluate the additive value of CI during EE in CAD diagnosis. METHODS Between 2000 and 2006, 4042 patients (1900 men with a mean age of 56 +/- 11 years) were e...

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Chronotropic incompetence: a never-ending story.

A clear association between chronotropic incompetence and increased mortality has been established by a variety of studies in patients with coronary artery disease as well as in healthy individuals. These results gave rise to speculation that rate responsive stimulation might improve prognosis in pacemaker (PM) patients with concomitant chronotropic incompetence. To date, however, no study was ...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1998

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(98)00377-5